Poly Arginine Coated Plates

Poly Arginine Coated Plates are specialized laboratory tools used in research and diagnostic applications. These plates are coated with poly-L-arginine, a positively charged synthetic polypeptide. The coating enhances cell adhesion and provides a uniform surface for immobilizing biomolecules, such as nucleic acids, proteins, or other macromolecules.

Content: 

Key Features and Characteristics

• Material and Structure:
  • Plates are typically made of polystyrene or other inert materials.
  • Coated with poly-L-arginine, known for its strong positive charge.
• Surface Charge:
  • The poly-L-arginine layer creates an electrostatically positive surface.
  • Promotes the attachment of negatively charged molecules like DNA, RNA, or proteins.
• Compatibility:
  • Suitable for a variety of assays, including ELISA, fluorescence imaging, and cell culture.
  • Compatible with most standard laboratory plate readers and imaging systems.
• Durability:
  • Stable under standard laboratory conditions.
  • Resistant to mild detergents and washing protocols.

Applications

• Molecular Biology:
  • Nucleic Acid Immobilization: The positive charge binds DNA or RNA for hybridization studies or PCR applications.
  • Protein Binding: Enables efficient protein attachment for enzyme-linked immunosorbent assays (ELISAs) or structural studies.
• Cell Culture:
  • Facilitates the adhesion of cells that typically require a charged surface for attachment, such as neuronal or endothelial cells.
  • Often used for specialized applications in tissue engineering and regenerative medicine.
• Drug Screening and Delivery Studies:
  • Used to test the interactions of drugs with immobilized biomolecules.
  • Useful in high-throughput screening platforms for drug discovery.
• Imaging and Microscopy:
  • Provides a uniform and stable platform for fluorescence imaging.
  • Ideal for studying cell morphology or molecular interactions.

Poly-arginine coated plates are indispensable tools in modern research, providing consistent, high-quality results in biomolecule immobilization, cell-based assays, and molecular diagnostics.